What is Bryan Johnson Blueprint?
Blueprint is Bryan Johnson's scientific self-experiment to slow and reverse biological ageing. Johnson, the tech entrepreneur who sold Braintree and Venmo for 800 million dollars in 2013, invests more than 2 million USD in total per year in the protocol, most of which goes to medical tests, advanced therapies and a team of 30 doctors and longevity experts.
The results he publishes are remarkable: his biological age has been reversed by 5.1 years, he ages biologically by only 0.69 years per calendar year, and his heart function matches that of a 37-year-old – even though he is 47. The Blueprint protocol is documented publicly and covers diet, exercise, sleep and supplements. In 2025 the protocol gained further attention through the Netflix documentary Don't Die: The Man Who Wants to Live Forever.
Want to understand the scientific principles behind ageing and cellular health? Read our guide to what longevity really means.
Bryan Johnson Blueprint – full supplement list 2026
Johnson's supplement routine is organised into three tiers: universal supplements suitable for most people, personalised supplements based on his biomarkers, and experimental interventions.
Blueprint Stack – Johnson's own product line
Blueprint Stack condenses his complex protocol into fewer products, with 74 compounds gathered in seven products. If you want to follow Johnson's protocol in full, you can buy a Blueprint Protocol Bundle with 30 products at 30% off – the most cost-effective way to get started.
- Essential Capsules – 24 core nutrients per dose, including B vitamins, Ubiquinol (CoQ10), lithium orotate and probiotics.
- Longevity Mix (powder) – A 13-ingredient blend with CaAKG, creatine, glutathione, glycine, magnesium, taurine and vitamin C.
- NAC + Ginger + Curcumin – NAC for antioxidant protection combined with the anti-inflammatory effects of curcumin.
- Omega-3 DHA/EPA (1,000–2,000 mg) – Cardiovascular health, brain function and inflammation.
Other daily supplements
- NAD+ / NMN / NR – Alternated 6 days per week. Johnson has measured an intracellular NAD+ value of 54.6 μM – within the optimal range of 40–100 μM. We offer NAD+ Noop (599 kr) as one of Blueprint's core products. Read more in our complete guide to NAD+ and NMN.
- Creatine (5 g) – Well-studied supplement for muscle mass, strength and cognitive function.
- Fisetin – Senolytic flavonoid that eliminates senescent "zombie cells". Available as Fisetin Novusetin 100 mg Swanson (399 kr).
- Luteolin – Anti-inflammatory flavonoid with neuroprotective properties.
- Lithium orotate (low dose) – NEW 2026 – Added to the protocol in 2026 following research showing a link between lithium levels in the brain and Alzheimer's. Johnson takes 5 mg daily. We now have a complete guide to lithium orotate and where you can buy Lithium Orotate 5 mg Swanson (299 kr).
- Vitamin D3 – Standardised supplement for immune function and bones. Available as Noop Vitamin D3 50 µg (2000 IU).
- Magnesium Glycinate – Supports sleep quality, muscle function and nerve transmission. We have Magnesium Glycinate Swanson (179 kr). Read more in our guide to which magnesium is best for sleep.
- Taurine (1–2 g) – Amino acid with documented benefits for cardiovascular health. Available as Taurine 500 mg Swanson (149 kr).
- CoQ10 / Ubiquinol – Mitochondrial energy production. Available as Ubiquinol 50 mg Swanson (399 kr).
- Lion's Mane – Medicinal mushroom for NGF stimulation and cognitive health. Johnson includes it for brain protection. Available as Lion's Mane 500 mg Swanson. Read more about nootropics for brain health.
- Tongkat Ali – For hormonal optimisation and testosterone support. Included in many biohackers' Blueprint-inspired stacks for hormonal health. Read our complete guide to tongkat ali.
- Turkesterone – Ecdysteroid for muscle performance and recovery. Read our guide to turkesterone for an honest review of the research.
Prescription medicines (require a doctor's prescription)
Part of Johnson's protocol consists of prescription medicines that should not be taken without a medical prescription:
- Acarbose (200 mg) – Slows carbohydrate absorption to counter blood sugar spikes.
- Metformin (500 mg) – Used in longevity circles for metabolic stability.
- Plasmalogens – Brain-supporting fats for memory protection.
What does Bryan Johnson Blueprint cost?
| Tier | What's included | Monthly cost |
|---|---|---|
| Blueprint Stack (official) | 74 compounds in 7 products | ~361 USD (~3,800 kr) |
| Full DIY | All supplements bought separately | ~600 USD (~6,300 kr) |
| Evidence-based core supplements | Creatine, omega-3, vitamin D, magnesium | 55–90 USD (~580–950 kr) |
| Johnson's total protocol | All tests, therapies, medical team | ~167,000 USD/month |
With us you'll find all Blueprint supplements gathered in one category.
Which supplements have the strongest scientific support?
- Creatine monohydrate – Hundreds of studies confirm effects on muscle mass, strength and cognitive function.
- Omega-3 DHA/EPA – Robust evidence for cardiovascular health and inflammation.
- Vitamin D3 – Most people in the Nordics are deficient; clear effects on immune function and bones.
- Magnesium – Broad study support for sleep, muscle function and heart health.
- NAD+ precursors (NMN/NR) – Clinical studies show that both effectively raise NAD+ levels. Read more in our complete NAD+ guide.
- Curcumin / Turmeric – Impressive anti-inflammatory properties.
- Taurine – Studies at 1–2 g/day show benefits for cardiovascular health.
- Lithium Orotate (microdose) – New 2026. A Harvard-led Nature study from 2025 links lithium levels in the brain to Alzheimer's risk. Read our guide to lithium orotate.
- Tongkat Ali – For testosterone and hormonal health. Read our complete guide to tongkat ali.
- Fadogia Agrestis – A complementary LH mechanism to tongkat ali. Read our guide to fadogia agrestis.
Can you follow Blueprint without spending a fortune?
Johnson's most important insight is that the lifestyle part of the protocol – sleep, diet and exercise – is free. His dietary principles include 2,250 calories per day, 130 g of protein and a plant-based diet without alcohol and processed food.
A realistic starting point:
- Optimise sleep, diet and exercise (free of charge)
- Take the evidence-based core supplements: creatine, omega-3, vitamin D, magnesium
- Add NAD+ precursors and Lion's Mane
- Consider lithium orotate 5 mg for neuroprotection
- Have regular blood tests to understand your biomarkers
Explore all of our longevity range for a complete selection. Also read our guide to nootropics for the cognitive part of a longevity protocol.
Frequently asked questions
How many supplements does Bryan Johnson take every day?
Johnson previously took more than 100 pills daily but has reduced this to 27–40 individual supplements. Blueprint Stack condenses 74 compounds into 7 products.
Which supplements did Bryan Johnson add in 2026?
In 2026 Johnson reduced NMN to six days per week, stopped taking Rapamycin and added low-dose lithium orotate and NDGA based on new research on lithium and brain health.
Are Blueprint supplements safe to take without a doctor?
The non-prescription parts – creatine, omega-3, vitamin D, magnesium, lion's mane, lithium orotate – are generally considered safe. Prescription parts such as Metformin and Acarbose should never be taken without a doctor's prescription.
Where can I buy the Blueprint supplements in Sweden?
At Noop you'll find a complete range of Blueprint supplements. We offer NAD+, fisetin, luteolin, lithium orotate, magnesium glycinate, lion's mane and more.
Summary
Bryan Johnson's Blueprint protocol is the most documented longevity experiment ever carried out publicly. His biomarkers – 5.1 years of reversed biological age – are hard to ignore.
The real insight is that the lifestyle part – consistent sleep, a plant-based diet and regular exercise – is free and probably the most important component. The supplements reinforce a good foundation; they do not replace it.
Ready to start? Take a look at the Blueprint range or read on about what longevity means and our guide to NAD+.