Bryan Johnson Blueprint: Supplements, Costs, and What You Can Copy
Bryan Johnson's Blueprint protocol includes over 40 daily supplements aimed at slowing biological aging. His own Blueprint Stack costs approximately $361 per month (~3,800 SEK), while a complete DIY setup with all the supplements he takes amounts to roughly $600/month (~6,300 SEK) – excluding diet and prescription medications.
What is Bryan Johnson Blueprint?
Blueprint is Bryan Johnson's scientific self-experiment to slow and reverse biological aging. Johnson, the tech entrepreneur who sold Braintree and Venmo for $800 million in 2013, invests over $2 million USD annually in the protocol, most of which goes to medical tests, advanced therapies, and a team of 30 doctors and longevity experts.
The results he publishes are remarkable: his biological age has been reversed by 5.1 years, he biologically ages by only 0.69 years per calendar year, and his heart function matches that of a 37-year-old – despite being 47. The Blueprint protocol is publicly documented and covers diet, exercise, sleep, and supplements. In 2025, the protocol gained further attention through the Netflix documentary Don't Die: The Man Who Wants to Live Forever.
Do you want to understand the scientific principles behind aging and cellular health? Read our guide on what longevity truly means.
Bryan Johnson Blueprint – complete supplement list 2026
Johnson's supplement routine is organized into three levels: universal supplements suitable for most, personalized supplements based on his biomarkers, and experimental interventions. Below are the main components divided by purpose.
Blueprint Stack – Johnson's own product line
Blueprint Stack condenses his complex protocol into fewer products with 74 compounds grouped into seven products. If you want to follow Johnson's complete protocol, you can purchase a Blueprint Protocol Bundle with 30 products at a 30% discount – the most cost-effective way to get started.
- Essential Capsules – 24 core nutrients per dose, including B-vitamins, Ubiquinol (CoQ10), Lithium Orotate, and probiotics. Supports energy, sleep, muscle repair, and cognitive function.
- Longevity Mix (powder) – A 13-ingredient blend with CaAKG, creatine, glutathione, glycine, magnesium, taurine, and vitamin C. Supports brain performance, energy metabolism, and muscle recovery.
- NAC + Ginger + Curcumin – NAC (N-acetylcysteine) for antioxidant protection combined with curcumin's anti-inflammatory effects. Johnson takes 2 grams of turmeric daily, divided into doses.
- Omega-3 DHA/EPA (1,000–2,000 mg) – From a low heavy metal source. Cardiovascular health, brain function, and inflammation.
Other daily supplements
- NAD+ / NMN / NR – Alternated 6 days per week. Johnson has measured an intracellular NAD+ level of 54.6 μM – within the optimal range of 40–100 μM. We offer NAD+ Noop (599 SEK) as one of Blueprint's core preparations. Read more in our guide to the best NAD+ supplements 2026.
- Creatine (5 g) – Well-studied supplement for muscle mass, strength, and cognitive function.
- Fisetin – Senolytic flavonoid that eliminates senescent "zombie cells." Available as Fisetin Novusetin 100 mg from Swanson (399 SEK).
- Luteolin – Anti-inflammatory flavonoid with neuroprotective properties, available as Luteolin 100 mg Swanson (249 SEK).
- Lithium Orotate (low-dose) – Added to the protocol in 2026. Supports brain health and cellular function. Available as Lithium Orotate 5 mg Swanson (299 SEK). We have also written a separate article about lithium orotate in Sweden – what it is and if it's legal.
- Vitamin D3 – Standardized supplement for immune function and bones. Available as Vitamin D3 2000 IU Swanson (119 SEK).
- Magnesium – Supports sleep quality, muscle function, and nerve transmission. We have Magnesium Glycinate from Swanson (179 SEK) – the same form Johnson uses. Read more in our guide on which magnesium is best for sleep.
- Taurine (1–2 g) – Amino acid with documented benefits for cardiovascular health. Available as Taurine 500 mg Swanson (149 SEK).
- CoQ10 / Ubiquinol – Mitochondrial energy production. Available as Ubiquinol 50 mg Swanson (399 SEK).
Prescription medications (require medical prescription)
Some parts of Johnson's protocol are prescription medications that should not be taken without medical prescription:
- Acarbose (200 mg) – Slows carbohydrate absorption to prevent blood sugar spikes after meals.
- Metformin (500 mg) – Used in longevity circles for metabolic stability and autophagy.
- Plasmologens (1 ml Glia + 1 ml Neuro) – Brain-supporting fats in liquid form for memory protection and cognitive aging.
In 2026, Johnson adjusted the protocol by reducing NMN frequency to six days a week, discontinuing Rapamycin, and adding low-dose lithium and NDGA for brain and cell function.
What does Bryan Johnson Blueprint cost?
The cost varies greatly depending on how closely you want to follow the protocol:
| Level | What's included | Monthly cost |
|---|---|---|
| Blueprint Stack (official) | Johnson's own product line, 74 compounds in 7 products | ~$361 USD (~3,800 SEK) |
| Complete DIY setup | All the supplements he takes, purchased separately | ~$600 USD (~6,300 SEK) |
| Evidence-based core supplements | Those with the strongest scientific support (creatine, omega-3, vitamin D, magnesium) | $55–90 USD (~580–950 SEK) |
| Johnson's total protocol | All tests, therapies, medical team, supplements | ~$167,000 USD/month |
A Reddit user who tried to replicate Johnson's protocol came up with an initial cost of $880 with a daily cost of approximately $20. With us, you can find all Blueprint supplements grouped into one category – including a bundle with 30 products at a 30% discount.
Which supplements have the strongest scientific support?
Johnson's protocol distinguishes between what is well-studied and what is more experimental. Supplements with the strongest scientific evidence include:
- Creatine monohydrate – Hundreds of studies confirm effects on muscle mass, strength, and cognitive function.
- Omega-3 DHA/EPA – Robust evidence for cardiovascular health and inflammation.
- Vitamin D3 – The majority in the Nordics are deficient; clear effects on immune function and bones.
- Magnesium – Broad study support for sleep, muscle function, and heart health.
- NAD+ precursors (NMN/NR) – Clinical studies show that both effectively raise NAD+ levels. Read more about how to increase NAD+ levels naturally.
- Curcumin / Turmeric – Impressive anti-inflammatory properties in clinical research.
- Taurine – Studies at 1–2 g daily show benefits for cardiovascular health and blood pressure.
More experimental supplements like fisetin and plasmologens show promising results in animal studies but have limited human data yet.
Can you follow Blueprint without spending a fortune?
Johnson's most important insight is that the lifestyle part of the protocol – sleep, diet, and exercise – is free and likely the most effective component. His dietary principles include 2,250 calories per day, 130 g of protein, and a plant-based diet without alcohol and processed foods.
A realistic starting point for someone who wants to draw inspiration from Blueprint:
- Optimize sleep, diet, and exercise (free of charge)
- Take the evidence-based core supplements: creatine, omega-3, vitamin D, and magnesium
- Add NAD+ precursors like NAD+ Noop if the budget allows
- Undergo regular health checks and blood tests to understand your own biomarkers
Explore our entire longevity range for a complete selection of supplements focused on a long and healthy lifestyle.
Frequently Asked Questions about Bryan Johnson Blueprint (FAQ)
How many supplements does Bryan Johnson take daily?
Johnson previously took over 100 pills daily but has reduced it to a more manageable setup with approximately 27–40 individual supplements. He has also created the Blueprint Stack, which condenses 74 compounds into 7 products to simplify the routine.
What is included in the Blueprint Stack?
The Blueprint Stack contains seven products: Essential Capsules, Longevity Mix (powder), Softgel with fat-soluble nutrients, NAC + Ginger + Curcumin, creatine, omega-3, and Snake Oil (extra virgin olive oil). With us, you can find a Blueprint Protocol Bundle with 30 Blueprint supplements at a great price.
Does it really cost $2 million per year?
Yes, but the majority of the cost is not supplements. It includes a medical team of 30 people, hundreds of biomarker tests per year, regular MRI scans, and advanced therapies. The supplement portion is about $361–600 per month.
What supplements did Bryan Johnson add in 2026?
In 2026, Johnson updated the protocol by reducing NMN to six days a week, discontinuing Rapamycin, and adding low-dose lithium orotate and NDGA for brain and cell function.
Are Blueprint supplements safe to take without a doctor?
The over-the-counter components – creatine, omega-3, vitamin D, and magnesium – are generally considered safe for most adults. Prescription components like Metformin and Acarbose should never be taken without a doctor's prescription. Combining many supplements without follow-up can lead to unpredictable interactions.
Where can I buy Blueprint supplements in Sweden?
At Noop, you'll find a complete range of Blueprint supplements with free shipping over €40. We offer the same products included in Johnson's protocol – including NAD+, fisetin, luteolin, lithium orotate, and magnesium glycinate – at competitive prices.
Summary: Is Blueprint worth it?
Bryan Johnson's Blueprint protocol is the most documented and transparent longevity experiment made public. His biomarkers – 5.1 years of reversed biological age and a biological aging rate of 0.69 years per calendar year – are hard to ignore.
The official Blueprint Stack at $361/month is a well-tested option for those who want to draw direct inspiration from Johnson's protocol. The real insight, however, is that the lifestyle component – consistent sleep, a plant-based diet, and six hours of exercise per week – is free and probably the most important component.
Ready to get started? Check out our Blueprint Protocol Bundle with 30% off or browse the entire Blueprint range to find the supplements that fit your budget and goals.